What Causes Lupus?

Updated at: Jul 27, 2015
What Causes Lupus?

The cause of lupus is unknown; though, a combination of genetics, hormones and environment have a certain role in its incidence.

Himanshu Sharma
Fashion & BeautyWritten by: Himanshu SharmaPublished at: Jul 27, 2015

Lupus is a chronic inflammatory illness in which body's immune system turns against its own tissues and organs. The condition can affect several body systems, including joints, skin, kidneys, blood cells, brain, heart and lungs. The most common symptoms of the condition include extreme fatigue, severe headaches, painful or swollen joints, anaemia, oedema, fever, butterfly-shaped rash across cheeks and nose, abnormal blood clotting, hair loss and many more.

Causes of lupus

The cause of lupus is unknown; although, a combination of genetics, hormones and environment have a certain role in the incidence. Those who have an inherited predisposition for lupus develop the disease after coming in contact with something in the environment trigger.


There is no specific gene or a group of genes to be considered responsible to cause lupus. The condition has appears to occur in certain families. For instance, when one of the twins has lupus, there is a high risk that the other twin will also develop the disease. The condition can also affect people with no family history of lupus. The scientists believe that disturbances or disorders of the human leukocyte antigen genes may be responsible for immune system's response, to cause lupus.


Your genes may decide the risk you have to develop lupus, but it takes environmental trigger to set off the illness or to bring on a flare. Some of the identified environmental triggers include:

  • ultraviolet rays from the sun,
  • radiations from fluorescent light bulbs,
  • sulfa drugs, sun-sensitizing tetracycline drugs,
  • an infection,
  • a cold or a viral illness,
  • exhaustion,
  • an injury,
  • emotional stress,
  • being pregnant and
  • giving birth.

Causes of lupus

Factors that may increase your risk of lupus include:

  • Lupus is more common in women.
  • Lupus can affect people of any age, although the illness is most often diagnosed between the ages of 15 and 40.
  • Lupus is reported more in the certain races, which include African Americans, Hispanics and Asians.

There are several medications available to manage the symptoms of lupus. As the medications have the certain risks and side-effects, therefore, so discuss the pros and cons of with your doctor beforehand.

Living a healthy lifestyle can help patients manage lupus. Understanding flares and taking preventative measures is one way to ward-off lupus’s complications. Health experts advocate the importance of wellness for those with lupus, including physical fitness, mental health and emotional well-being. For normal, fulfilling and hassle-free life, all you have to do is exercise regularly, eat healthy, relax and maintain responsive communication with your doctor.

Image source: Getty Images



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