• shareIcon

Sugar Overload can cause Heart Damage

Latest By PTI , PTI / Jun 18, 2013
Sugar Overload can cause Heart Damage

Your sweet tooth may be damaging your heart, warns study.

Berry tartsAccording to the researchers at The University of Texas Health Science Center at Houston (UTHealth), eating too much sugar can set people down a pathway to heart failure.

A single small molecule, the glucose metabolite glucose 6-phosphate (G6P), causes stress to the heart that changes the muscle proteins and induces poor pump function leading to heart failure. G6P can accumulate from eating too much starch and/or sugar, researchers said.

As per the researchers, physicians can give diuretics to control the fluid but treatment is difficult. Heinrich Taegtmeyer, principal investigator and professor of cardiology at the UTHealth Medical School, said that they still have these terrible statistics and no new treatment for the past 20 years to support it.

The research panel performed preclinical trials in animal models, as well as tests on tissue taken from patients at the Texas Heart Institute, who had a piece of the heart muscle removed in order to implant a left ventricle assist device. Both led to the discovery of the damage caused by G6P.

Apart from this, the study has given hope for new treatments. Two drugs, rapamycin (an immunosuppressant) and metformin (a diabetes medication) disrupt signalling of G6P and improved cardiac power in small animal studies, they said.

The study was published in the Journal of the American Heart Association.



Read more Health News




All possible measures have been taken to ensure accuracy, reliability, timeliness and authenticity of the information; however Onlymyhealth.com does not take any liability for the same. Using any information provided by the website is solely at the viewers’ discretion. In case of any medical exigencies/ persistent health issues, we advise you to seek a qualified medical practitioner before putting to use any advice/tips given by our team or any third party in form of answers/comments on the above mentioned website.

This website uses cookie or similar technologies, to enhance your browsing experience and provide personalised recommendations. By continuing to use our website, you agree to our Privacy Policy and Cookie Policy. OK