Prognosis of Sarcoidosis

Prognosis of Sarcoidosis

Prognosis of sarcoidosis in most cases is good though on initial presentation, predicting the prognosis of sarcoidosis can be extremely difficult. Most people with sarcoidosis have mild disease that may resolve on its own or with treatment.

Sarcoidosis, most often, affects young people between the age group of 20-29 years. As the disease can affect one or multiple parts of the body, it is often misdiagnosed as some other condition. The natural questions for any person diagnosed with the condition are "What is it?" and "Will it get better?" The exact cause of the disease is not known, but in most cases, the prognosis is good. On initial presentation, however, predicting the prognosis of sarcoidosis can be extremely difficult.

Prognosis of Sarcoidosis

Most people with sarcoidosis have mild disease, which may resolve on its own or with treatment. It usually does not leave any lasting effects and is likely to go into remission. A few patients may have severe and unremitting disease, which causes progressive damage to multiple organs. Complications may develop in 20-25% of patients.

Many people may have the disease and may not even be aware of it. This may be because the disease is symptomless and is discovered by chance or the symptoms are very mild. A person with severe symptoms should not wait for spontaneous resolution of symptoms. If you have bothersome symptoms, it is best to seek the best medical care you can get.

In most cases, the lungs are affected (about 90 percent of the cases have lung involvement). People, who have stage I or stage II changes on chest radiograph, usually improve spontaneously or with treatment. In patients with spontaneous improvement of symptoms, relapse is very unusual. Chance of improvement in patients with stage III disease on cheats X-ray is not very pleasant. About 10 to 15 percent of the patients with lung involvement continue to suffer from extreme symptoms. These patients remain symptomatic and suffer from this disease chronically until the day they die.

Some factors that can influence the outcome of sarcoidosis

Favourable prognostic factors

  • White race.
  • Löfgren's syndrome.
  • Stage I changes on chest radiograph.

Unfavourable prognostic factors

  • Black race.
  • Age >40 years.
  • Organomegaly.
  • Lupus pernio.
  • Cardiac disease.
  • Kidney involvement.
  • Sinus involvement.
  • Bone involvement.


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