Researchers in the University of North Carolina in Orange County have conducted a study in which it was found that anti-AIDS drugs fail to disengage reservoirs of HIV present in the immune system. The anti-cancer drug is found potent to purge hidd
An anti-cancer drug is found potent to purge hidden virus in patients receiving HIV treatment, researchers of University of North Carolina in Orange County, North Carolina have claimed.
The researchers conducted a study in which it was found that anti-AIDS drugs fail to disengage reservoirs of HIV present in the immune system. Due to this, deadly HIV infection becomes active once a patient discontinues his medications. For complete cure of AIDS, flushing out HIV reservoirs is of crucial significance. The study was published on July 25, 2012 in a scientific journal, Nature.
This study was collaboration between the Harvard School of Public Health, National Cancer Institute and the University of California. The tested drug was vorinostat which is used to treat some types of lymphoma (cancer of the lymphatic system). The scientists undertook various experiments to evaluate how vorinostat activates the dormant HIV and how it disrupts HIV storehouse.
After a successful laboratory test, vorinostat was given to eight HIV-infected men, who were responding to the anti-AIDS treatment and their roused HIV levels were compared to their levels prior to anti-cancer medication.
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